Neutralization of Unfractionated Heparin and Low Molecular Weight Heparin by Novel Salicylamide Derivatives
نویسندگان
چکیده
منابع مشابه
Unfractionated and low molecular weight heparin
Background Unfractionated heparin (UFH) is mostly obtained from porcine and bovine mucosa and has been widely used for the treatment and prevention of thrombotic events. It consists of molecular chains of various lengths varying from 2000 to 40,000 Da [1]. Low molecular weight heparins (LMWHs) are smaller chains of UFH that can be obtained, from unfractionated heparin, by various chemical and e...
متن کاملCost-effectiveness of low-molecular-weight heparin and unfractionated heparin in treatment of deep vein thrombosis.
BACKGROUND Acute deep vein thrombosis has traditionally been treated with unfractionated heparin (UFH), administered intravenously, but low-molecular-weight heparins (LMWH), administered subcutaneously, have recently become available. The authors sought to determine which therapy was more cost-effective for inpatient and outpatient treatment of deep vein thrombosis. METHODS An incremental cos...
متن کاملComparison of low-molecular-weight heparin (enoxaparin sodium) and standard unfractionated heparin for haemodialysis anticoagulation.
BACKGROUND Low-molecular-weight heparin (LMWH) has been suggested as providing safe, efficient, convenient and possibly more cost-effective anticoagulation for haemodialysis (HD) than unfractionated heparin, with fewer side-effects and possible benefits on uraemic dyslipidaemia. METHODS In this prospective, randomized, cross-over study we compared the safety, clinical efficacy and cost effect...
متن کاملLow-Molecular-Weight Heparin and Unfractionated Heparin Decrease Th-1, 2, and 17 Expressions
BACKGROUND We evaluated the effects of T helper cell differentiation in a mite-allergic animal model treated with inhaled heparins of different molecular weight. METHOD BALB/c mice were divided into four groups: 1. Control, 2. Mite intratracheal (mIT), 3. Inhaled heparin (hIN), 4. Inhaled low-molecular-weight heparin (lmwhIN). Groups 2, 3, and 4 were sensitized twice with Der p allergen subcu...
متن کاملHeparin and low-molecular-weight heparin.
Heparin is one of the oldest biological medicines, and has an established place in the prevention and treatment of venous thrombosis. Low-molecular-weight heparins (LMWH) have been developed by several manufacturers and have advantages in terms of pharmacokinetics and convenience of administration. They have been shown to be at least as effective and safe as unfractionated heparin and have repl...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.1118.5